A padrão of continuous (daily or almost daily) uso of synthetic cathinones that has caused damage to a person’s physical or mental health or has resulted in behaviour leading to harm to the health of others. The padrão of continuous synthetic cathinone uso is evident over a period of at least one month. Harm to health of the individual occurs due to one or more of the following: (1) behaviour related to intoxicação; (2) direct or secondary toxic effects on body organs and systems; or (3) a nocivo route of administration. Harm to health of others includes any form of physical harm, including trauma, or mental transtorno that is directly attributable to behaviour related to synthetic cathinone intoxicação on the part of the person to whom the diagnosis of nocivo uso of synthetic cathinones applies.