A syndrome that involves significant cognitive features that do not fulfill the diagnostic requirements of any of the specific Transtornos neurocognitivos and are judged to be a direct pathophysiological consequence of a health condition or injury not classified under mental and behavioural transtornos (e.g., cognitive changes due to a brain tumour), based on evidence from the history, physical examination, or laboratory findings. This category should be used in addition to the diagnosis for the presumed underlying transtorno or disease when the cognitive symptoms are sufficiently grave to warrant specific clinical attention.