Demência due to psychoactive substances including medications includes forms of Demência that are judged to be a direct consequence of substance uso and that persist beyond the usual duration of action or abstinência syndrome associated com the substance. The amount and duration of substance uso must be sufficient to produce the cognitive impairment. The cognitive impairment is not better accounted for by a transtorno that is not induced by substances such as a Demência due to another medical condition.