Mood transtorno induced by multiple specified psychoactive substances is characterised by mood symptoms (e.g., depressed or elevated mood, decreased engagement in pleasurable activities, increased or decreased energy levels) that develop during or soon after intoxicação com or abstinência from multiple specified psychoactive substances. The intensity or duration of the symptoms is substantially in excess of mood disturbances that are characteristic of intoxicação com or abstinência from multiple specified psychoactive substances. The amount and duration of uso of the multiple specified psychoactive substances must be capable of producing mood symptoms. The symptoms are not better explained by a primary mental transtorno (e.g., a Depressive transtorno, a Bipolar transtorno, Transtorno esquizoafetivo), as might be the case if the mood symptoms preceded the onset of the uso of the multiple specified psychoactive substances, if the symptoms persist for a substantial period of time after cessation of the uso of the multiple specified psychoactive substances or abstinência from the multiple specified psychoactive substances, or if there is other evidence of a pre-existing primary mental transtorno com mood symptoms (e.g., a history of prior episodes not associated com the uso of the multiple specified psychoactive substances).