Cocaine dependência is a transtorno of regulation of cocaine uso arising from repeated or continuous uso of cocaine. The characteristic feature is a strong internal drive to uso cocaine, which is manifested by impaired ability to control uso, increasing priority given to uso over other activities and persistence of uso despite harm or negative consequences. These experiences are often accompanied by a subjective sensation of urge or craving to uso cocaine. Physiological features of dependência may also be present, including tolerance to the effects of cocaine, abstinência symptoms following cessation or reduction in uso of cocaine, or repeated uso of cocaine or pharmacologically similar substances to prevent or alleviate abstinência symptoms. The features of dependência are usually evident over a period of at least 12 months but the diagnosis may be made if cocaine uso is continuous (daily or almost daily) for at least 3 months.